Second Tranche of BARDA Funding Supports Diagnostic Designed to Read Immune System and Rapidly Diagnose Acute Infection at Point of Care

Key Takeaways

  • Inflammatix a pioneering molecular diagnostics company, announced today a contract extension of $7.4 million from the Biomedical Advanced Research and Development Authority.
  • The new funding will support continued development and commercialization of Inflammatix’s sample-to-answer, point-of-care MyrnaTM test system, which is designed to read RNA using machine learning and produce results in under 30 minutes.

Burlingame, Calif., October 29, 2020  — Inflammatix a pioneering molecular diagnostics company, announced today a contract extension of $7.4 million from the Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services’ Office of the Assistant Secretary for Preparedness and Response, to further develop its point-of-care test and system to diagnose infection by reading the immune system. The contract is part of a BARDA contract worth up to $72 million, if all options are exercised.

The new funding will support continued development and commercialization of Inflammatix’s sample-to-answer, point-of-care MyrnaTM test system, which is designed to read RNA using machine learning and produce results in under 30 minutes, as well as continued development of the ViraBac EZTM test (formerly known as HostDx Fever), which reads gene expression patterns in the immune system to identify whether a suspected infection is bacterial or viral, enabling physicians to quickly and accurately determine when to prescribe antibiotics. The test will use a fingerstick collection and capillary blood sample, and is designed for use in primary care, urgent care and other outpatient clinical settings.

One of the biggest threats to global health today is antibiotic resistance. Increasing and incorrect antibiotic use leads to antibiotic-resistant bacteria that become more difficult and costly to treat, and more deadly. Today, an estimated 30 percent of antibiotics are inappropriately prescribed to patients because their infections are not obviously bacterial or viral in origin.1 In addition, almost three million Americans each year become infected with bacteria that are resistant to antibiotics, with more than 35,000 dying as a direct result.2 New diagnostic methods that can help better direct antibiotics to only those patients that need them will be an important element in combatting antibiotic resistance, ensuring that proven therapies can continue to fight disease and save lives.

“We are pleased to continue to partner with BARDA in the development of our ViraBac EZ test and Myrna instrument. Enabling physicians to make more informed decisions about which patients need antibiotics and which can avoid them has the potential to transform patient care at the point of care,” said Tim Sweeney, M.D., Ph.D., co-founder and chief executive officer of Inflammatix.

“In the physician’s office, current methods for diagnosing infections are slow, produce inconsistent results, and/or do not provide the information we need to confidently prescribe treatment,” said David Lin, MD, family medicine specialist with Sutter Health, Sacramento, California. “Having a test that allows us to quickly make more informed decisions about which patients are infected and could benefit from antibiotics would have a meaningful impact on patient care.”

Key Takeaways

  • Inflammatix a pioneering molecular diagnostics company, announced today a contract extension of $7.4 million from the Biomedical Advanced Research and Development Authority.
  • The new funding will support continued development and commercialization of Inflammatix’s sample-to-answer, point-of-care MyrnaTM test system, which is designed to read RNA using machine learning and produce results in under 30 minutes.

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Quotes

We are pleased to continue to partner with BARDA in the development of our ViraBac EZ test and Myrna instrument. Enabling physicians to make more i...
Tim SweeneyCo-founder and CEO

Related Bios

Tim Sweeney, MD, PhD
Co-Founder and CEO
Tim completed his MD/PhD at Duke University, and then spent time training in the general surgery residency program at Stanford University. While training as a surgeon, he became frustrated with the current diagnostic tools for infection. During his residency research years, he completed a postdoc MS in Biomedical Informatics, during which he worked with Dr. Khatri to identify a new way to diagnose infections based on ‘reading’ the immune system. Their work designing custom informatics algorithms for sifting through heterogeneous large datasets led to the core technology on which Inflammatix is based.
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Jonathan Romanowsky
Co-Founder and Chief Business Officer
Jonathan is driven by the incredible impact that diagnostics can provide dedicated healthcare professionals to improve patient care while providing significant value to public and private payers paying for it. He has served in commercial leadership roles at Telomere Diagnostics, Veracyte, CardioDx and CareDx. He has successfully brought product concepts through launch and to achieve standard-of-care status. He has led numerous commercialization efforts in product management, marketing, operations, reimbursement and sales in the United States and abroad. Previously, Jonathan pioneered electronic prescribing at iScribe (now part of CVS) and was a business strategy consultant for Bain & Company. Jonathan earned his Bachelor of Science in Political Economy from the University of California, Berkeley and his MBA from Stanford University, focusing on medical technology innovation.
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